Search results for " PET-CT"

showing 3 items of 3 documents

Whole-body diffusion weighted MR and FDG-PET/CT in Hodgkin lymphoma: predictive role before treatment and early assessment aftrer two courses of chem…

2017

To evaluate whether whole-body MR has a predictive role before treatment and may asses the response after two courses of chemotherapy in comparison to FDG-PET/CT

Settore MED/36 - Diagnostica Per Immagini E Radioterapialymphoma MR-Diffusion/Perfusion PET-CT
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Genotyping analysis and 18FDG uptake in breast cancer patients: a preliminary research

2013

Background: Diagnostic imaging plays a relevant role in the care of patients with breast cancer (BC). Positron Emission Tomography (PET) with 18F-fluoro-2-deoxy-D-glucose (FDG) has been widely proven to be a clinical tool suitable for BC detection and staging in which the glucose analog supplies metabolic information about the tumor. A limited number of studies, sometimes controversial, describe possible associations between FDG uptake and single nucleotide polymorphisms (SNPs). For this reason this field has to be explored and clarified. We investigated the association of SNPs in GLUT1, HIF-1a, EPAS1, APEX1, VEGFA and MTHFR genes with the FDG uptake in BC. Methods: In 26 caucasian individu…

OncologyCancer Researchmedicine.medical_specialtyPathologydbSNPGenotypePET-CTSingle-nucleotide polymorphismStandardized uptake valueBreast NeoplasmsGene mutationMultimodal ImagingPolymorphism Single NucleotideBreast cancerBreast cancerFluorodeoxyglucose F18Internal medicinemedicineHumansPET-CTSUVpvcbiologybusiness.industryResearchGlucose analogSUVmaxSingle nucleotide polymorphismsmedicine.diseaseSingle nucleotide polymorphismBreast cancer Single nucleotide polymorphisms PET-CT SUVmax SUVpvcOncologyMethylenetetrahydrofolate reductasePositron-Emission Tomographybiology.proteinFemaleRadiopharmaceuticalsbusinessTomography X-Ray Computed
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Metabolic impact of Partial Volume Correction of [18F]FDG PET-CT oncological studies on the assessment of tumor response to treatment

2014

AIM: The aim of this work is to evaluate the metabolic impact of Partial Volume Correction (PVC) on the measurement of the Standard Uptake Value (SUV) from [18F]FDG PET-CT oncological studies for treatment monitoring purpose. METHODS: Twenty-nine breast cancer patients with bone lesions (42 lesions in total) underwent [18F]FDG PET-CT studies after surgical resection of breast cancer primitives, and before (PET-I) and after (PET-II) chemotherapy and hormone treatment. PVC of bone lesion uptake was performed on the two [18F]FDG PET-CT studies, using a method based on Recovery Coefficients (RC) and on an automatic measurement of lesion metabolic volume. Body-weight average SUV was calculated f…

Settore ING-INF/05 - Sistemi Di Elaborazione Delle InformazioniPhantoms ImagingReproducibility of ResultsAntineoplastic AgentsBone NeoplasmsBreast NeoplasmsMiddle AgedMultimodal ImagingBone and bonePositron-emission tomography Standardized uptake value Partial volume correction bone metastases therapy monitoringFluorodeoxyglucose F18[18F]FDG PET-CT oncologicalHumansRadiographic Image Interpretation Computer-AssistedFemaleNeoplasm MetastasisPositron-emission tomographyTomography X-Ray ComputedNeoplasm metastasiAged
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